Lingual tonsils hypertrophy and possibility of its correction by physical factors
Alexander Andreev1, Sergey Puhlik1, Oleg Melnikov1, Irina Tagunova2, Sergey Gushcha2
1Odessa National Medical University, Ukraine
2State Institution "Ukrainian Research Institute of Medical Rehabilitation Therapy of Ministry of Health of Ukraine", Odessa, Ukraine
Abstract
Introduction: The component of the lymphopharyngeal ring is the lingual tonsil (LT), located on the root of the tongue. With pathological changes in the lymphoid tissue of the pharynx, surgical removal of the tonsils, as a result of increased antigenic load, a compensatory increase in LT is observed – «lingual tonsillar hypertrophy». This is observed against the background of age-related involutive changes, when the remaining elements of the lymphopharyngeal ring begin to perform anti-antigenic and adaptive activity. The processes taking place in, the structure of the LT, which is familiar to the body, changes - the receptor apparatus creates pathological impulses from the organ. The severity of clinical manifestations correlates with the degree of increase in LT. The emphasis on these manifestations, psychosomatic conditions, create a complex of pathological sensations that violate the quality of patients’ life. The goal and objectives of the study are aimed at improving the quality of patients’ life with lingual tonsil hypertrophy (LTH), by developing effective methods of diagnosis and treatment, assessing the role of the immunoregulatory shift in the pathogenesis of LTH of the possibility of their correction by the action of a physical factor (cold destruction).
Materials and methods: When examining 850 people who underwent complex research and instrumental diagnostics in connection with the pathology of ENT organs, 119 people (the main group) were diagnosed with different degrees of LTH, with control of 30 healthy people. Cryosurgical treatment was offered to 76 patients who used the method for treating of lingual tonsil hypertrophy by cryodestruction using a hook-shaped applicator with a heat-insulating nozzle on the back surface, an individual polyethylene cap, and a cryoapparatus.
Results and discussions: With LTH, an increase in the volume and mass of tissues forming the morphological basis of the tonsil was detected: the main substance was an increase in the number and size of layers of coarse fibrous fibers, fields of fat cells, and the growth of mucous glands. The mucous membrane, thinning, undergoes dystrophic-degenerative changes. The rate of proliferation correlates with the severity of inflammation, the causes of which are multifactorial, individual. There is an increased sensitivity reaction to microbial and household allergens, an increase in the content of antibodies in the blood to LT tissues, a change in microbiocinosis of the pharyngeal mucosa, and vegetation of non-resident microflora. As a result of cryosurgical treatment in 56 (73.68%) cases, a decrease in the volume of LT tissue was observed. The deep layers, partially absorbed, were replaced by healthy tissues, the surface layers were rejected with the formation of an atrophic scar or regenerate, the structure of which was close to organotypic. The cause of pathological impulse was eliminated, clinical indicators were normalized, the quality of life of patients was improved.
Conclusions: LTH should be considered as a continuation of the development of a productive process associated with immunoregulatory changes in chronic infectious and allergic conditions. Local cryogenicity on LTH was accompanied by normalization of the structure of its own substance, LT, and a decrease in inflammatory changes in surrounding tissues. The development of inflammatory changes in LT was a local manifestation of a general disturbance in the functioning of the immune defense system. Achieving a persistent positive effect in the treatment of LTH requires an integrated approach with mandatory systemic immune correction and hormonal correction.
Key words: lingual tonsil hypertrophy, cryosurgery, immunoregulatory shift, obstructive sleep apnea
Correction of magnesium deficiency in the body with balneological means: experimental studies
GUSHCHA Sergey1, PLAKIDA Alexander2, NASIBULLIN Boris1, VOLYANSKA Veronica1, SAVITSKYІ Ivan2, GLADKІY Tatyana3
1State Institution "Ukrainian Research Institute of Medical Rehabilitation Therapy ofMinistry of Health of Ukraine", Odessa, Ukraine
2Odessa National Medical University, Odessa, Ukraine
3Odessa National University State after I.I. Mechnikov, Odessa, Ukraine
Abstract. In the modern world, a lack of magnesium in the body is one of the most common deficient conditions in humans. Low levels of magnesium have been associated with a number of chronic diseases. This work is devoted to the study of the effect of the use of the balneological means "Magnesium oil" for the correction of the manifestations of experimentally induced magnesium deficiency. The experiment was conducted on 50 white female rats of the Wistar auto-breeding line which were divided into 3 equal groups: (1) control, (2) model of magnesium deficiency, (3) received "Magnesium oil". As a result of modeling the state of magnesium deficiency, significant changes are observed in the central nervous system, vegetative nervous system, and kidneys of animals. The use of balneological means "Magnesium oil" can significantly reduce the negative manifestations of magnesium deficiency.
НОВІ МОЖЛИВОСТІ ЛІКУВАННЯ РЕФРАКТЕРНОЇ ГАСТРОЕЗОФАГЕАЛЬНОЇ РЕФЛЮКСНОЇ ХВОРОБИ
ДУ «Український НДІ медичної реабілітації та курортології МОЗ України» (м. Одеса)
Драгомирецька Н. В., Заболотна І. Б., Гуща С. Г., Калініченко М. В., Іжа Г. М.
Зв’язок публікації з плановими науково-дослідними роботами. Робота є фрагментом НДР «Розробити немедикаментозні методи відновлювального лікування хворих на гастроезофагеальну рефлексну хворобу із супутньою патологією органів травлення» (№ державної реєстрації 0118U000356).
Physiological mechanisms of influence of table and treatment mineral waters based on the balgeneological measure “Magnesium Oil” on some systems of health organism in experiment
Gushcha SG, Nasibullin BA, Plakida AL, Volyanskaya VS
1. Ukraine Research Institute of Medical Rehabilitation and Balneology of the Ministry of Health of Ukraine, Ukrainе
2. Odessa National Medical University, Ukraine
Non-alcoholic fatty liver disease and mineral waters of Ukraine – opportunities of application (experimental-clinical studies)
Zabolotna Irina, Gushcha Sergey., Mikhailenko Vladimir
1. State Institution «Ukrainian Scientific-Research Institute of Medical Rehabilitation and Balneology, the Ministry of Public Health of Ukraine», Odessa.
2. Department of Medical Rehabilitation Odessa National Medical University, Odessa, Ukraine
Pathogenetic and Sanogenetic Mechanisms of the Influence of Mineral Waters (Siliconed and with Increased Organic Substances) of Different Osmularity on the Exposure of Toxic Nephritis
S.G. Gushcha, B.A. Nasibullin, A.L. Plakida, V.N. Kalinichenko, L.V. Tikhokhod, T.V. Mohylevska
1. Institute Research of Medical Rehabilitation and Balneology of the Ministry of Health of Ukraine, Odessa, Ukraine
2. Odessa National Medical University, Odessa, Ukraine
Metabolic Syndrome: The Corrective Effect of Mineral Water with an Increased Content of Organic Substances
Sergey Gushcha, Boris Nasibullin, Alexander Plakida, Veronika Volyanska, Irina Balashova, Tatyana Mohylevska
1. Department of Fundamental Research, State Institution «Institute Research of Medical Rehabilitation and Balneology of the Ministry of
Health of Ukraine», Odessa, Ukraine
2. Department of Physical Rehabilitation, Sports Medicine, Physical Training and Valeology, Odessa National Medical University, Odessa, Ukraine
3. Department of General Practice and Family Medicine, Odessa National Medical University, Odessa, Ukraine
Hepatoprotective Action of Boric Mineral Waters in Toxic Hepatosis: Experimental Study
Sergey Gushcha, Boris Nasibullin, Alexander Plakida, *, Veronika Volyanska, Tatyana Gladkiy, Irina Balashova
1. Department of Fundamental Research, State Institution «Institute Research of Medical Rehabilitation and Balneology of the Ministry of Health of Ukraine», Odessa, Ukraine
2. Department of Physical Rehabilitation, Sports Medicine, Physical Training and Valeology, Odessa National Medical University, Odessa, Ukraine
3. Biological Faculty, Odessa Mechnikov National University State, Odessa, Ukraine
4. Department of General Practice and Family Medicine, Odessa National Medical University, Odessa, Ukraine
INVESTIGATION OF THE INFLUENCE OF MINERAL WATER WITH INCREASED CONTENT OF ORGANIC ON THE DEVELOPMENT OF METABOLIC SYNDROME IN THE EXPERIMENTINVESTIGATION OF THE INFLUENCE OF MINERAL WATER WITH INCREASED CONTENT OF ORGANIC ON THE DEVELOPMENT OF METABOLIC SYNDROME IN THE EXPERIMENT
Gushcha, S.G., Nasibullin B.A., Plakida A.L., Babova I.K., Balashova I.V., Trubka I.A., Volyanska, V.S. and Kalinichenko N.V.
Comprehensive Assessment of Functional Changes in the Organism of Healthy Rats in External and Internal Use of Silicone Low-Mineralized Mineral Water
Sergey Gushcha, Boris Nasibullin, Alexander Plakida, *, Irina Trubka, Veronika Volyanskaya, Nikolay Kalinichenko, Irina Balashova
Журнал клінічних та експериментальних медичних досліджень / 2017;5(1):713–719
COMPLEX ASSESSMENT OF PARAMETER CHANGES OF HOMEOSTASIS IN RATS WITH EXPERIMENTAL GASTRITES
КОМПЛЕКСНА ОЦІНКА ЗМІНИ ПАРАМЕТРІВ ГОМЕОС-ТАЗУ ЩУРІВ ПРИ ЕКСПЕРИМЕНТАЛЬНОМУ ГАСТРИТІ
S.Gushcha, B.Nasibullin, E.Bakholdina, A.Oleshko, N.Kalinichenko
Б.А.Насібуллін, С.Г.Гуща, О.І.Бахолдіна, О.Я.Олешко, М.В.Калініченко
